ml141 cdc42 inhibitor Search Results


ml 141  (Bio-Techne corporation)
95
Bio-Techne corporation ml 141
Ml 141, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ml 141/product/Bio-Techne corporation
Average 95 stars, based on 1 article reviews
ml 141 - by Bioz Stars, 2026-03
95/100 stars
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ml141  (Merck & Co)
90
Merck & Co ml141
Combined effects of <t>Cdc42</t> activity and Diaph2 depletion on MT-dynamics. HT29 control and Diaph2-depleted cells were treated with 20 µM <t>ML141</t> for 2 h, DMSO served as vehicle control. Thereafter, the cells were fixed and stained with antibodies against β-tubulin and detyrMTs, coupled with Alexa-fluor568 or Alexa-fluor488, respectively. The fluorescence intensity derived from these antibodies was analyzed by ImageJ from 10 different cells from one representative experiment out of 4 and the ratio between detyrMTs to MTs was calculated. Shown are mean values + SD. Values were normally distributed, evaluated with One-Way ANOVA and Bonferroni’s multiple comparison test, *p < 0.05, **p < 0.01 and ***p < 0.001.
Ml141, supplied by Merck & Co, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ml141/product/Merck & Co
Average 90 stars, based on 1 article reviews
ml141 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier

Image Search Results


Combined effects of Cdc42 activity and Diaph2 depletion on MT-dynamics. HT29 control and Diaph2-depleted cells were treated with 20 µM ML141 for 2 h, DMSO served as vehicle control. Thereafter, the cells were fixed and stained with antibodies against β-tubulin and detyrMTs, coupled with Alexa-fluor568 or Alexa-fluor488, respectively. The fluorescence intensity derived from these antibodies was analyzed by ImageJ from 10 different cells from one representative experiment out of 4 and the ratio between detyrMTs to MTs was calculated. Shown are mean values + SD. Values were normally distributed, evaluated with One-Way ANOVA and Bonferroni’s multiple comparison test, *p < 0.05, **p < 0.01 and ***p < 0.001.

Journal: Scientific Reports

Article Title: The formin Drosophila homologue of Diaphanous2 (Diaph2) controls microtubule dynamics in colorectal cancer cells independent of its FH2-domain

doi: 10.1038/s41598-019-41731-y

Figure Lengend Snippet: Combined effects of Cdc42 activity and Diaph2 depletion on MT-dynamics. HT29 control and Diaph2-depleted cells were treated with 20 µM ML141 for 2 h, DMSO served as vehicle control. Thereafter, the cells were fixed and stained with antibodies against β-tubulin and detyrMTs, coupled with Alexa-fluor568 or Alexa-fluor488, respectively. The fluorescence intensity derived from these antibodies was analyzed by ImageJ from 10 different cells from one representative experiment out of 4 and the ratio between detyrMTs to MTs was calculated. Shown are mean values + SD. Values were normally distributed, evaluated with One-Way ANOVA and Bonferroni’s multiple comparison test, *p < 0.05, **p < 0.01 and ***p < 0.001.

Article Snippet: In order to stimulate Cdc42 activity, the Cdc42/Rac1 GTPase inhibitor ML141 (Merck, Calbiochem # 217708) was used (see also Hong et al . ).

Techniques: Activity Assay, Staining, Fluorescence, Derivative Assay